This book was an interesting foray into how we age and what it would mean for humanity if we were to increase our lifespan. It had the biology of how aging works, complete with easy-to-understand diagrams, as well as the social aspects of living decades past our current lifespans. I loved learning about the author and his research as well as his opinions on how we as individuals might live life if we were able to stay healthy for a long, long time.

The actual biology behind increased lifespans is a bit complicated, and I would be lying if I said that I understood all of it as I read. However, Sinclair's scientific writing was still easy enough to follow (even if there were complicated biology names included) and I ended up learning a lot about how these types of experiments and theses are conducted. While these parts weren't the most engaging, I still give the author credit for attempting to explain his life's work in layman's terms.

My favorite aspect of the book was thinking about the societal affects that increased longevity would have in humans. It was fascinating learning about what that would mean in terms of the world's resources, politics, and ethics, as well as smaller scale ideas like marriage and pets. A lot of the thought experiments that Sinclair wrote about could be base ideas for sci-fi novels which I greatly appreciated.

All in all, if you like biology and learning about what humans are capable of, I would recommend this book. There is a lot to learn about our species and this book highlights some of the best (and worst) parts of humanity.
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Compelling read, with plenty of information about healthy aging and longevity. Obviously, thee is revolutionary research going on with longevity. I am hesitant about the book because of possible conflicts of interest from the author's commercial interests. He presents results as if they are actionable, and they are not. There are plenty of researchers working in this space, there are many intriguing developments, but little has been settled beyond eating a healthy diet and exercise.

Amazing! I am now trying to convince all my friends and family to read this.

After reading this book I immediately implemented several of his suggestions re. lifestyle changes and supplements. And a few weeks in I already feel better. I mean obviously that is not a scientific result, and it's hard to know how much of what I feel is a placebo. But I received a complement at work the other day about my new increased positive energy. And when I wake up in the morning my joints don't click and crunch the way they used to while they warmed up for the day. So time will tell how useful this is in the long term. But for now I am feeling pretty good!

The other more general outcome of this book is that it made me feel less dread about the aging process. Even if NMN and Resveratrol don't turn out to be the miracles they seem to be. I feel confident that with so much promising research going on, someone is going to find something that works in the near future. And old age won't have to be the hell that it has been for so many of the previous generations.




Highly optimistic approach of writing. Even in this chaos-centric world, this book gives us a ray of hope, explaining that the world that we are living in, is a way better one compared with the prior versions of life on this planet.  

David Sinclair visualised a world where the common man can rarely dream of. He traveled like a crazy man through paths that no one else traveled.  His vision to make the world a better place by increasing the Lifespan of human beings is a highly applaudable scientific research. Author says, achieving longevity is not an impossible thing, nations need to consider aging as a disease and they need to invest more on this subject. Imagine a world where our children can see and experience wisdom from their great great great grandparents. 
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Very positive take on aging. Not your typical self help book- takes a macro look at aging and challenges our assumptions and our healthcare system. A small mention at the end for what supplements and activities will extend life - although brief are very helpful if you are looking to improve the quality of your health span!
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This book deals with the author's research and hypothesis of aging: essentially, that there is a somewhat centralized cause and that we (scientists) are learning more and more about that cause at a rapid pace--and thus, real, data-backed treatment for aging may become possible in the near future. The author describes how, very soon, it may be common for people to have not only longer lifespans, but (crucially) longer health spans. We may be able to treat the symptoms of growing old such that living healthy into ones 90s or 100s becomes the norm.

Now, I've seen online that this author gets somewhat lambasted for being outspoken about the topic and also for possible conflicts of interest related to his involvement in the patents and companies that are related to his research findings. For sure, it is necessary to tread lightly when one is a researcher, and to take limited findings with a grain of salt as a consumer. But I feel that the author has done a good job addressing this issue in the book and presenting his opinions in a tempered, unbiased fashion. The scientist in him is measured; the human in him is optimistic.

There are compounds sold as supplements on the market today that claim to reverse or halt aging. These are not US FDA approved or regulated in the way medicines are. Why? This comes to the catch-22 presented by the author in his book:

Aging is not classified as a disease, and therefore, it is incredibly hard to fund research and especially clinical trials on aging as opposed to, say, related diseases like Alzheimer's, type 2 diabetes, or heart disease. Yet, "living longer" is a huge risk factor for developing these diseases. Why not study the root cause and try to head all age-related diseases off at the pass? This is one of the author's main points that he bemoans: Why shouldn't we treat aging itself as a disease?

Overall, the book doesn't get a higher rating from me because it is somewhat repetitive and does steer a bit close to "preachy" for me at times. But the topics raised here are very important for society to consider. Scientific research will not stop, and we'd better be ready to face the changes that may need to be made if people start living longer, healthier lives. Will people retire at 65 and be looking at 40 more years of health? Would they start second careers? Would politicians in this class stay in power for 6 or more decades--and if so, is that good or bad? Would only rich people get anti-aging treatment? The list goes on.

Granted, it all seems pie-in-the-sky, but oftentimes technological advances come out of places we least expect. With the accelerating pace of medical understanding over the past 30 years, who is to say what the next 30 might bring?
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